This course is offered under the program of the HKUST Summer Institute for Secondary School Students by the School of Science. This course aims to offer an overview of fundamental concepts in quantitative biology, including biological numeracy, biophysical laws and quantitative research methodologies. Concepts such as stoichiometry, energies, forces, information and dynamics will be introduced to help students develop an intuition for the spatiotemporal scales of various biological entities and processes. Quantitative reasoning is at the core of all topics covered. Guided by examples from both classic and contemporary scientific findings, students will learn to move beyond phenomenological descriptions and (re)think biology in terms of quantitative and generalizable principles. Along the way, students will cultivate an appreciation for numbers, equations, and math models as effective tools for describing, comprehending, and predicting living systems.