This advanced course is designed for graduate students with prior experience in blockchain technology and artificial intelligence. It will explore the intersection of these two transformative fields, focusing on the synergistic potential of AI agents within the cryptocurrency market. The course will provide an in-depth analysis of existing projects that leverage AI and blockchain, highlighting innovative applications and the significant impact of large-scale initiatives that seamlessly integrate LLM-powered AI agents and cryptocurrency. By the end of the course, participants will be equipped with the knowledge and skills to conceptualize and develop impactful projects at this crucial intersection. Students should seek approval from the course instructor to take this reading course.