Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 5 Gender Equality -
SDG 6 Clean Water and Sanitation -
SDG 7 Affordable and Clean Energy -
SDG 8 Decent Work and Economic Growth -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 11 Sustainable Cities and Communities -
SDG 12 Responsible Consumption and Production -
SDG 13 Climate Action -
SDG 14 Life Below Water -
SDG 15 Life on Land -
SDG 16 Peace, Justice and Strong Institutions -
SDG 17 Partnerships for the Goals
Fingerprint
Dive into the research topics where Division of Life Science is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Guojun BU, 卜國軍
- Division of Life Science - Head and Chair Professor, Lo Ka Chung Charitable Foundation Professor of Science
Person: HKUST Staff
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Hao CHEN, 陳浩
- Department of Computer Science and Engineering - Assistant Professor
- Department of Chemical and Biological Engineering - Assistant Professor
- Division of Life Science - Assistant Professor
Person: HKUST Staff
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Tom CHEUNG, 張曉東
- Division of Life Science - Associate Head and Professor, S H Ho Professor of Life Science
Person: HKUST Staff
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King Lau CHOW, 周敬流
- Department of Chemical and Biological Engineering - Professor
- Academic Registry - Academic Registrar
- Division of Public Policy - Professor
- Division of Life Science - Professor
Person: HKUST Staff
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Neuropsychiatric symptoms in cognitive progression and Alzheimer’s disease Continuum: biomarker discovery using plasma proteomics
WONG, H. Y. (CoI), FU, K. Y. (CoI), IP, N.Y.-Y. (PI), JIANG, Y. (CoI) & ZUO, L. (CoI)
Shanghai Medical Innovation & Development Foundation
1/06/26 → 31/05/30
Project: Research
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Molecular Mechanisms of Replisome Coupling
TYE, B.-K. (Team member), LEUNG, D. C. Y. (CoPI), DANG, S. (CoPI), LI, X. (CoPI) & ZHAI, Y. (PI)
RGC - Collaborative Research Fund
1/06/26 → 31/05/29
Project: Research
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Human centromere structure and its maintenance mechanism
ZHAI, Y. (CoPI)
RGC - Collaborative Research Fund
1/02/26 → 31/01/29
Project: Research
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Do mechanosensitive TMC1/2 channels moonlight as lipid scramblases?
HUANG, P. (PI) & CHEN, Y. (CoI)
1/01/26 → 31/12/28
Project: Research
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Deciphering the role of TREM2 in microglial lysosome dynamics and Alzheimer's pathogenesis
CHEN, X. (PI) & BU, G. (PI)
National Natural Science Foundation of China (NSFC) / Research Grants Council (RGC)
1/01/26 → 31/12/29
Project: Research
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An integrated technology platform for next- generation cancer immunotherapy - from identification of tumor neoantigens to development of novel therapeutic vaccine modalitie
WANG, J. (CoPI) & ZHAO, Y. (PI)
1/01/26 → 31/12/30
Project: Research
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Impedance-Activated Mitochondria Sorter Driven by Machine Learning
KO, R. K. M. (CoI) & YOBAS, L. (PI)
1/01/26 → 31/12/28
Project: Research
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Primary ciliary dyskinesia diagnosis by advanced light microscopy
CHEN, Y. (CoI), CHEN, H. (CoI) & LIU, Z. (PI)
1/01/26 → 31/12/28
Project: Research
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Centre for Plant Vacuole Biology and Biotechnology
ZHAI, Y. (CoPI)
1/01/26 → 31/12/30
Project: Research
Research output
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3D SA-LoIFM: A three-dimensional framework for segmentation-assisted learning of informative feature matching in liver CT-3D US rigid registration
He, B., Wu, T., Zhang, Y., Luo, H., Chen, H. & Jia, F., 1 Jun 2026, In: Biomedical Signal Processing and Control. 118, 109664.Research output: Contribution to journal › Journal Article › peer-review
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A bispecific antibody designed to act as a NRP2/PLXNA1 agonist mimics anticancer activity of SEMA3F
Tian, H., Fung, C. P., Burman, L., Chong, Y. E., Liu, C., Geng, Y., Yang, L., Chow, M. W., Zhang, Y., Ho, K. W. H., Zhu, G., Wu, Z., Yang, X. L., Xu, Z. & Nangle, L. A., Feb 2026, In: Journal of Biological Chemistry. 302, 2, 111056.Research output: Contribution to journal › Journal Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
A Breast Vision Pathology Foundation Model for Real-world Clinical Utility
Xu, Y., Zhang, Z., Zhang, X., Xu, M., Zhou, F., Wang, Y., Ma, J., Xin, Y., Li, D., Lu, C., Cen, Z., Tan, Y., Yao, Q., Wang, Q., Gao, Z., Zhang, Y., Chen, J., Liu, F., Xu, Q. & Dai, Y. & 15 others, , 6 May 2026, 60 p.Research output: Working paper › Preprint
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Acceleration Practices for Gifted Learners in Hong Kong SAR China
YUEN, M., LEUNG, A. Y. N., CHOW, K. L., WONG, J., WONG, C.-P., CHAN, S., FENG, J., ZHANG, J. & DATU, J. A. D., 11 Feb 2026, International Perspectives on Acceleration in Gifted Education. Roberts, J. L. & Clark, T. (eds.). 1 ed. New York: Routledge, p. 38-48 11 p.Research output: Chapter in Book/Conference Proceeding/Report › Book Chapter › peer-review
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A chemically synthesized resveratrol dimer is a potent inhibitor of vascular endothelial growth factor (VEGF).
LIN, S., GUO, S., TANG, W. L., YE, Y., HO, Y. M., DUAN, R., LEUNG, K. W., ZHOU, J., DONG, T. & TSIM, K. W. K., 20 Mar 2026, In: Archives of Clinical and Biomedical Research. 10, 2, p. 108-116 9 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
A class of COPI cargo receptors regulates processing of transmembrane proteins by reinforcing their Golgi retention
Gao, J., Cong, C., Wu, Y., Xiang, Y., Yan, B., Jia, Q., Yao, Z. P., Guo, Y. & Hu, J., 27 Jan 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 4, e2512723123.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
A conserved ER protein prevents lipotoxicity by stimulating the key enzyme in glycerolipid synthesis
LI, Y., HUANG, S., CHAN, L. S., LI, X., To, N. S., Zhao, X., JUNG, K., YANG, X., TSE, Y. C., Xu, N., Xia, Y., CHEUNG, T., QU, J. & MAK, H. Y., 7 May 2026, In: Nature Communications. 17, 1, 78 p., 6165.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Active pixel power control for crosstalk-free All-optical neural interrogation
YAN, G., TIAN, G., FU, Y., HE, Y., SHE, Z., Chen, K. K. Y., SEMMELHACK, J. & QU, J., 11 Feb 2026, In: Nature Communications. 13 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin
You, Y., Suen, M. C., Miao, H., Geng, Y., Din, R. U., Yuan, M., Xue, Q., Li, X., Xu, N., Guo, Z., Lam, H. M., Lo, K. W., Liu, C. & Zhu, G., 15 Jul 2026, In: Chemistry - A European Journal. 12 p., e71389.Research output: Contribution to journal › Journal Article › peer-review
Open Access
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Investigating Cytoplasmic DNA (CytoDNA) in Response to Impaired DNA Damage Repair
LAM, T. K. (Contributor)
11 Nov 2026Activity: Talk or presentation › Contributed
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Characterizing the role of human endogenous retroviruses in totipotent-pluripotent transition
KAN, Y. H. (Contributor)
15 May 2026Activity: Talk or presentation › Contributed
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Asia Pacific Drosophila Neuroscience Conference 4
LAM, Y. H. (Participant)
20 Apr 2026 → 24 Apr 2026Activity: Participating in or organising an event › Conference / Workshop
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A Dynamic Mechanism of Working Memory Through Slow Branches
LUO, Z. (Speaker)
11 Mar 2026 → 17 Mar 2026Activity: Talk or presentation › Contributed
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Protein-based classification reveals an immune-hot subtype of IDH mutant astrocytoma with worse prognosis
TANG, J. (Invited speaker)
16 Jan 2026Activity: Talk or presentation › Invited
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Loss of RPGR disrupts motile cilia and causes primary ciliary dyskinesia by affecting F-actin dynamics
LIU, Z. (Invited speaker)
16 Jan 2026Activity: Talk or presentation › Contributed
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Two Distinct Vesicle Pools of Spontaneously Recycled Inhibitory Synaptic Vesicles
PARK, H. K. (Invited speaker)
12 Jan 2026 → 14 Jan 2026Activity: Talk or presentation › Contributed
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Two Distinct Vesicle Pools of Spontaneously Recycled Inhibitory Synaptic Vesicles
PARK, H. K. (Invited speaker)
8 Jan 2026 → 9 Jan 2026Activity: Talk or presentation › Invited
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Traffic (Journal)
GAO, J. (Ad Hoc Referee)
2026 → …Activity: Publication peer-review and editorial work › Editorial work
Awards
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Best Poster Award, the 48th annual meeting of MBSJ
TSUI, L. W. (Recipient), 3 Feb 2026
Prize: Other Research Award and Prize
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Best Presentation Award 2nd Prize at HKUST Life Science Postgraduate Student Seminar
LU, J. (Recipient), 12 May 2026
Prize: Other Research Award and Prize
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HKUST RedBird Academic Excellence Award for Continuing PhD Students in 2025-26
LI, J. (Recipient), 4 May 2026
Prize: Research Fellowship
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HKUST RedBird Academic Excellence Award for Continuing PhD Students in 2025-26
ZHAO, X. (Recipient), May 2026
Prize: Other Research Award and Prize
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Press/Media
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13 HKUST Research Projects Secure Top Funding from RGC Collaborative Research Fund and Research Impact Fund
WANG, D., WANG, S., CHEN, S., TSANG, C. W., ZHAI, Y., ZHANG, F., LI, M., MENG, Z., WANG, G., YANG, Y., LU, H., LI, X. & CHENG, K.-T. T.
7/01/26
1 item of Media coverage
Press/Media
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HKUST Researchers Uncover Key Transport Mechanisms in Cells, Shedding Light on Causes of Genetic Diseases
30/12/25
1 item of Media coverage
Press/Media
Courses
Datasets
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Original Data Regarding "Gap Junction-transported cAMP from the Niche Controls Stem Cell Progeny Differentiation"
TU, R. (Owner), DataSpace@HKUST, 5 Jul 2023
Dataset
Student theses
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[Gamma]-Aminobutyric AcidA receptor [alpha]1 subunit : hyperexpression, purification, structural characterization and ligand binding
Hang, J. (Author), 2000Student thesis: Doctoral thesis
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<span class="ql-cursor"></span>Rbp9 Regulates Germline Stem Cell Differentiation as a Translational Regulator in the Drosophila Ovary
ZHENG, M. (Author), XIE, T. (Supervisor), 2025Student thesis: Master's thesis
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3D-Printed Microfluidic Interconnects for High-Throughput Bio-MEMS Applications
XU, Q. (Author), GUO, Y. (Supervisor) & LEE, S.-W. (Supervisor), 2025Student thesis: Doctoral thesis
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AAV-mediated Gene Therapy Halts Retinal Degeneration in Mouse Model of Retinal Detachment by Targeting Serpina3n
CHEN, W. (Author), 2025Student thesis: Master's thesis
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AAV-mediated Gene Therapy Halts Retinal Degeneration in Mouse Model of Retinal Detachment by Targeting Serpina3n
CHEN, W. (Author), XIE, T. (Supervisor), 2025Student thesis: Master's thesis
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A behavioural paradigm for investigating depth perception in zebrafish larvae
CHAN, W. (Author), SEMMELHACK, J. L. (Supervisor), 2021Student thesis: Master's thesis
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A behavioural paradigm for investigating depth perception in zebrafish larvae
LI, Y. (Author), 2019Student thesis: Master's thesis
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Acetylcholine regulates melanogenesis of retinal pigment epithelia (RPE) cells : a non-neuronal function of cholinergic system in retina
KONG, I. (Author), TSIM, K. W. K. (Supervisor), 2023Student thesis: Master's thesis
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Acetylcholinesterase regulates melanogenesis in skin : a regulator for sunlight-induced skin pigmentation
WU, Q. (Author), 2020Student thesis: Doctoral thesis