Projects per year
Personal profile
Research interests
Biotechnology - Computational Medicine and Health Informatics
Biotechnology - Protein engineering
Biotechnology - Biomaterials
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Related documents
Education/Academic qualification
PhD in Bioengineering, PhD, Stanford University
2018
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Collaborations and top research areas from the last five years
Projects
- 2 Active
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Engineering Novel Adeno-associated Viral Vectors (AAVs) for Therapeutic Modulation of Microglial Function
ZHU, B. D. (PI)
1/01/26 → 31/12/28
Project: Research
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Spatiotemporally engineering of macrophage for translational applications topic 2: Development of Advanced Gene-editing Strategies for Efficient Macrophage Reprogramming In vitro and In vivo
ZHU, B. D. (CoI), SUN, M. (CoI) & WANG, X. (CoI)
1/12/24 → 30/11/29
Project: Research
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An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammatory CAR macrophages in renal cell carcinoma
Jing, W., Han, M., Wang, G., Kong, Z., Zhao, X., Fu, Z., Jiang, X., Shi, C., Chen, C., Zhang, J., Zheng, Z., Gao, J., Sun, W., Tang, C., Yang, Z., Wang, Y., Liu, Y., Zhao, K., Zhu, D. & Shi, B. & 1 others, , May 2025, In: Nature Cancer. 6, 5, p. 838-853 16 p., 69.Research output: Contribution to journal › Journal Article › peer-review
13 Citations (Scopus) -
Engineering CAR-T Therapeutics for Enhanced Solid Tumor Targeting
Zhu, D., Kim, W. J., Lee, H., Bao, X. & Kim, P., 12 Jun 2025, In: Advanced Materials. 37, 23, 2414882.Research output: Contribution to journal › Review article › peer-review
5 Citations (Scopus) -
Rejuvenation Modulation of Nucleus Pulposus Progenitor Cells Reverses Senescence-Associated Intervertebral Disc Degeneration
Zhao, D. W., Zhang, J., Chen, C., Sun, W., Liu, Y., Han, M., Zhang, Y., Fu, Z., Shi, C., Zhao, X., Yang, Z., Tang, C., Zhao, K., Zhu, D., Zhang, Y., Cheng, L. & Jiang, X., 19 Feb 2025, In: Advanced Materials. 37, 7, 2409979.Research output: Contribution to journal › Journal Article › peer-review
17 Citations (Scopus) -
mRNA-Laden Lipid-Nanoparticle-Enabled in Situ CAR-Macrophage Engineering for the Eradication of Multidrug-Resistant Bacteria in a Sepsis Mouse Model
Tang, C., Jing, W., Han, K., Yang, Z., Zhang, S., Liu, M., Zhang, J., Zhao, X., Liu, Y., Shi, C., Chai, Q., Li, Z., Han, M., Wang, Y., Fu, Z., Zheng, Z., Zhao, K., Sun, P., Zhu, D. & Chen, C. & 6 others, , 23 Jan 2024, In: ACS Nano. 18, 3, p. 2261-2278 18 p.Research output: Contribution to journal › Journal Article › peer-review
44 Citations (Scopus) -
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy
Zhu, D., Brookes, D. H., Busia, A., Carneiro, A., Fannjiang, C., Popova, G., Shin, D., Donohue, K. C., Lin, L. F., Miller, Z. M., Williams, E. R., Chang, E. F., Nowakowski, T. J., Listgarten, J. & Schaffer, D. V., Jan 2024, In: Science Advances. 10, 4Research output: Contribution to journal › Journal Article › peer-review
Open Access33 Citations (Scopus)