Projects per year
Personal profile
Research interests
Biotechnology - Computational biology
Biotechnology - Protein engineering
Biotechnology - Gene and cell therapy
Related documents
Education/Academic qualification
PhD in Bioengineering, PhD, Stanford University
2018
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 6 Active
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Engineering Novel Adeno-associated Viral Vectors (AAVs) for Therapeutic Modulation of Microglial Function
ZHU, B. D. (PI)
1/01/26 → 31/12/28
Project: Research
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SIAT-HKUST Joint Laboratory for Brain Science
ZHU, B. D. (PI), CHEN, H. (Team member), WANG, J. (Team member) & MIAO, Y. (Team member)
1/01/26 → 31/12/26
Project: Research
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Neuroimmune Mechanisms and Modulation in Alzheimer’s Disease
WU, A. R. (CoI), FU, K. Y. (CoPI), IP, N.Y.-Y. (CoPI), ZHU, B. D. (CoI), QU, J. (CoI), BU, G. (PI), LING, G. S. (CoI), CHOW, H. M. (CoI), KO, H. (CoPI), IP, Y. M. B. (CoI), WANG, J. (CoPI), LIU, K. (CoPI), LUI, K.O.-L. (CoPI), WANG, S. (CoPI) & MOK, V. C. T. (CoI)
RGC - Theme-based Research Scheme
1/01/26 → 31/12/30
Project: Research
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State Key Laboratory of Nervous System Disorders (SKLNSD)
WU, A. R. (CoI), WU, Z. (CoI), FU, K. Y. (CoPI), HUANG, P. (CoI), IP, N.Y.-Y. (PI), WONG, Y. H. (CoI), ZHU, B. D. (CoI), QU, J. (CoI), BU, G. (CoI), WANG, J. (CoI), CHEN, H. (CoI), LIU, K. (CoPI), YANG, C. (CoI), TANG, B. (CoI) & CHEUNG, T. (CoI)
Innovation and Technology Commission
1/07/25 → …
Project: Research
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An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammatory CAR macrophages in renal cell carcinoma
Jing, W., Han, M., Wang, G., Kong, Z., Zhao, X., Fu, Z., Jiang, X., Shi, C., Chen, C., Zhang, J., Zheng, Z., Gao, J., Sun, W., Tang, C., Yang, Z., Wang, Y., Liu, Y., Zhao, K., Zhu, D. & Shi, B. & 1 others, , 29 Apr 2025, In: Nature Cancer. 6, 5, p. 838-853 16 p.Research output: Contribution to journal › Journal Article › peer-review
42 Link opens in a new tab Citations (Scopus) -
Engineering CAR-T Therapeutics for Enhanced Solid Tumor Targeting
Zhu, D., Kim, W. J., Lee, H., Bao, X. & Kim, P., 12 Jun 2025, In: Advanced Materials. 37, 23, 18 p., 2414882.Research output: Contribution to journal › Review article › peer-review
20 Link opens in a new tab Citations (Scopus) -
Rejuvenation Modulation of Nucleus Pulposus Progenitor Cells Reverses Senescence-Associated Intervertebral Disc Degeneration
Zhao, D. W., Zhang, J., Chen, C., Sun, W., Liu, Y., Han, M., Zhang, Y., Fu, Z., Shi, C., Zhao, X., Yang, Z., Tang, C., Zhao, K., Zhu, D., Zhang, Y., Cheng, L. & Jiang, X., 19 Feb 2025, In: Advanced Materials. 37, 7, 15 p., 2409979.Research output: Contribution to journal › Journal Article › peer-review
34 Link opens in a new tab Citations (Scopus) -
mRNA-Laden Lipid-Nanoparticle-Enabled in Situ CAR-Macrophage Engineering for the Eradication of Multidrug-Resistant Bacteria in a Sepsis Mouse Model
Tang, C., Jing, W., Han, K., Yang, Z., Zhang, S., Liu, M., Zhang, J., Zhao, X., Liu, Y., Shi, C., Chai, Q., Li, Z., Han, M., Wang, Y., Fu, Z., Zheng, Z., Zhao, K., Sun, P., Zhu, D. & Chen, C. & 6 others, , 23 Jan 2024, In: ACS Nano. 18, 3, p. 2261-2278 18 p.Research output: Contribution to journal › Journal Article › peer-review
79 Link opens in a new tab Citations (Scopus) -
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy
Zhu, D., Brookes, D. H., Busia, A., Carneiro, A., Fannjiang, C., Popova, G., Shin, D., Donohue, K. C., Lin, L. F., Miller, Z. M., Williams, E. R., Chang, E. F., Nowakowski, T. J., Listgarten, J. & Schaffer, D. V., Jan 2024, In: Science Advances. 10, 4Research output: Contribution to journal › Journal Article › peer-review
Open Access48 Link opens in a new tab Citations (Scopus)
Activities
- 2 Invited
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Sparking the gene therapy revolution with AI
ZHU, B. D. (Invited speaker)
Aug 2025Activity: Talk or presentation › Invited
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Evolving synthetic viruses: sparking the gene therapy revolution with AI
ZHU, B. D. (Invited speaker)
17 May 2025Activity: Talk or presentation › Invited