Personal profile
Research interests
Biological Sciences - Neuroscience
Health Sciences - Immunology
Education/Academic qualification
PhD in Immunology, PhD, National University of Singapore
2019
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Neuropsychiatric symptoms in cognitive progression and Alzheimer’s disease Continuum: biomarker discovery using plasma proteomics
WONG, H. Y. (CoI), FU, K. Y. (CoI), IP, N.Y.-Y. (PI), JIANG, Y. (CoI) & ZUO, L. (CoI)
Shanghai Medical Innovation & Development Foundation
1/06/26 → 31/05/30
Project: Research
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Deciphering the Factors of Longevity through a Multi-Omics Study in Long-Lived Individuals in Hong Kong
WONG, H. Y. (CoPI), FU, K. Y. (CoPI), IP, F. C. F. (CoPI), IP, N.Y.-Y. (PI) & MOK, K. Y. B. (CoPI)
Bright Future Charitable Foundation Limited
1/12/25 → 31/12/29
Project: Research
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Explainable AI for Early Prediction of Alzheimer's Disease Using Proteomics and Clinical Data
WONG, H. Y. (CoI), FU, K. Y. (PI), IP, N.Y.-Y. (CoPI) & LV, G. (CoI)
1/06/25 → 31/05/26
Project: Research
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A Randomized-Controlled Trial of Trazodone on Reducing Plasma sST2 Level and Neurodegeneration Progression in Patients with Amnestic Mild Cognitive Impairment and Obstructive Sleep Apnea
WONG, H. Y. (CoI), FU, K. Y. (CoI), IP, F. C. F. (CoI), IP, N.Y.-Y. (PI), HUI, C. Y. (CoI), NG, S.S.-S. (CoI) & KWOK, T. C. Y. (PI)
Innovation and Technology Commission, Morningside Life Science Limited
4/10/21 → 3/10/24
Project: Research
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Development Of A Blood-based Proteome Biomarker Panel For Alzheimer's Disease In Chinese
WONG, H. Y. (CoI), CHAN, L. T. A. (CoI), FU, K. Y. (CoI), IP, F. C. F. (CoI), IP, N.Y.-Y. (PI), KWOK, T. C. Y. (CoI) & MOK, V. C. T. (CoI)
Innovation and Technology Commission
1/06/21 → 31/05/24
Project: Research
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Ethnic-specific effects of the LILRB2–LILRB5 locus and newly identified risk loci for Alzheimer's disease in the East Asian population
Japanese Alzheimer's Disease Neuroimaging Initiative & Alzheimer's Disease Neuroimaging Initiative, Feb 2026, In: Alzheimer's and Dementia. 22, 2, 16 p., e71219.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification
Jiang, Y., Zheng, W., Xia, Z., Wong, W. W., Cheng, L. K. W., Ip, F. C., Choi, S. M., Chan, A. L. T., Lam, C. Y., Ho, K. S., Shum, C. K., Yuen, J. K. Y., Shea, Y. F., Wai, H. M., Mok, V. C. T., Kwok, T. C. Y., Mok, K. Y., Wong, H. Y., Zetterberg, H. & Fu, A. K. Y. & 1 others, , 10 Mar 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 10, 10 p., e2536792123.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Targeted blood proteome profiling using NULISAseq identifies a high-performance biomarker panel for Aβ pathology quantification and staging
Zheng, W., Jiang, Y., Wong, H. Y., Wong, W. W., Cheng, L. K. W., Cheng, E. Y. L., Wong, B. W. Y., Lo, R. M. N., Leung, S. K., Ip, F. C., Yuen, J. K. Y., Shea, Y. F., Wong, W. M., Shum, C. K., Wai, H. M., Mok, V. C. T., Kwok, T. C. Y., Mok, K. Y., Heslegrave, A. & Hardy, J. & 3 others, , Feb 2026, In: Alzheimer's and Dementia. 22, 2, 17 p., e71179.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Interferon-induced GTP-binding protein MX1 drives hyperexcitability in peripheral nerves: a novel mechanism in small fiber neuropathy
Chan, A. C. Y., Huang, H., Shah, A., Zhang, B., Foo, N. W. J., Li, R., Mohammad Rizal, N. A. B., Wong, H. Y., Teoh, H. L., Mak, A., Soong, T. W., Sharma, V. K. & Schwarz, H., 1 Oct 2025, In: Journal of Neuroinflammation. 22, 1, 16 p., 219.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
The TREM2 H157Y variant is associated with more severe neurodegeneration in Alzheimer's disease and altered immune-related processes
Tsui, J. S. M., Au, D. M., Uhm, H., Wong, W. W., Lo, R. M. N., Jiang, Y., Ip, F. C. F., Mok, K. Y., Wong, H. Y., Kwok, T. C. Y., FU, K. Y. & Ip, N. Y., Sept 2025, In: Alzheimer's and Dementia. 21, 9, e70586.Research output: Contribution to journal › Journal Article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus)