Projects per year
Personal profile
Research interests
Biological Sciences - Cellular and molecular mechanisms
Biological Sciences - Neurodegenerative disease
Position Held
Associate Director of Daniel and Mayce Yu Molecular Neuroscience Center
Associate Director of Brain and Intelligence Research Institute
Education/Academic qualification
PhD in Biology, PhD, The Hong Kong University of Science and Technology
1998
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Neuropsychiatric symptoms in cognitive progression and Alzheimer’s disease Continuum: biomarker discovery using plasma proteomics
WONG, H. Y. (CoI), FU, K. Y. (CoI), IP, N.Y.-Y. (PI), JIANG, Y. (CoI) & ZUO, L. (CoI)
Shanghai Medical Innovation & Development Foundation
1/06/26 → 31/05/30
Project: Research
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Neuroimmune Mechanisms and Modulation in Alzheimer’s Disease
WU, A. R. (CoI), FU, K. Y. (CoPI), IP, N.Y.-Y. (CoPI), ZHU, B. D. (CoI), QU, J. (CoI), BU, G. (PI), LING, G. S. (CoI), CHOW, H. M. (CoI), KO, H. (CoPI), IP, Y. M. B. (CoI), WANG, J. (CoPI), LIU, K. (CoPI), LUI, K.O.-L. (CoPI), WANG, S. (CoPI) & MOK, V. C. T. (CoI)
RGC - Theme-based Research Scheme
1/01/26 → 31/12/30
Project: Research
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Deciphering the Factors of Longevity through a Multi-Omics Study in Long-Lived Individuals in Hong Kong
WONG, H. Y. (CoPI), FU, K. Y. (CoPI), IP, F. C. F. (CoPI), IP, N.Y.-Y. (PI) & MOK, K. Y. B. (CoPI)
Bright Future Charitable Foundation Limited
1/12/25 → 31/12/29
Project: Research
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NeuroCare Community Project
FU, K. Y. (CoI), IP, N.Y.-Y. (PI), WONG, W. Y. (CoI), WONG, J.C.-H. (CoI), MOK, K. Y. B. (CoPI), KWAN, R. (CoI), LAM, S. (CoI) & CHEUNG, T. (CoI)
1/10/25 → 30/09/30
Project: Research
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The NeuroCare Community Project – Revolutionizing Early Alzheimer's Disease Detection
FU, K. Y. (CoI), IP, N.Y.-Y. (PI), WONG, W. Y. (CoI), WONG, J.C.-H. (CoI), MOK, K. Y. B. (CoPI), LAM, S. (CoI), CHEUNG, T. (CoI) & KWAN, R. (CoI)
1/07/25 → 30/06/30
Project: Research
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Circular RNA circHomer1 mediates hippocampal functions via ribonucleoprotein granule transport and dendritic targeting of synaptic RNAs
Cai, Y., Zheng, Z., Xu, H., Zhu, Y., Zepeda, J. C., Grueter, B. A., Wang, X., Ku, T., Duan, Y., Tsang, H. W. S., Fu, W. Y., Fu, A. K. Y., Mellios, N., Wong, H. H. W., Lai, K. O. & Ip, J. P. K., 13 Feb 2026, In: Science Advances. 12, 7, 20 p., eads7509.Research output: Contribution to journal › Journal Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
DeepPlaque: a scalable multimodal platform for Aβ pathology and cell analysis in Alzheimer’s disease
Wong, H. Y., Jin, C., Yuen, S. L., Yang, X., Gill, S. S., Xu, J., Lai, K. P. E., Fu, W. Y., Gao, W., Wang, X., Wang, J., Cao, H., Lv, G., Mok, K. Y., Tian, R., Fu, A. K. Y., Chen, H. & Ip, N. Y., 21 Jul 2026, In: EMBO Molecular Medicine. 22 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Ethnic-specific effects of the LILRB2–LILRB5 locus and newly identified risk loci for Alzheimer's disease in the East Asian population
Japanese Alzheimer's Disease Neuroimaging Initiative & Alzheimer's Disease Neuroimaging Initiative, Feb 2026, In: Alzheimer's and Dementia. 22, 2, 16 p., e71219.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification
Jiang, Y., Zheng, W., Xia, Z., Wong, W. W., Cheng, L. K. W., Ip, F. C., Choi, S. M., Chan, A. L. T., Lam, C. Y., Ho, K. S., Shum, C. K., Yuen, J. K. Y., Shea, Y. F., Wai, H. M., Mok, V. C. T., Kwok, T. C. Y., Mok, K. Y., Wong, H. Y., Zetterberg, H. & Fu, A. K. Y. & 1 others, , 10 Mar 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 10, 10 p., e2536792123.Research output: Contribution to journal › Journal Article › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
Mutant independent allele specific CRISPR targeting strategy for treating gene diseases: [China]
FU, K. Y. (Inventor), IP, N. Y. Y. (Key Inventor), DUAN, Y. (Inventor) & FU, Y. (Inventor), 24 Apr 2026, IPC No. C12N 15/10, A61K 48/00, A61P 25/28, C12N 15/90, 13 Sept 2024, Priority date 14 Sept 2023, Priority No. US63/582,523Research output: Patent
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Regulatory roles of soluble ST2 in microglial state transition and functions in Alzheimer’s disease
FU, K. Y. (Invited speaker)
15 Nov 2025 → 19 Nov 2025Activity: Talk or presentation › Contributed
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Investigating the pathologic mechanisms of familial Alzheimer’s disease using iPSC-derived neuron models.
FU, K. Y. (Invited speaker)
15 Nov 2025 → 19 Nov 2025Activity: Talk or presentation › Contributed
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Transcriptional regulatory mechanisms underlying IL-33-stimulated microglial state transition in Alzheimer’s disease
FU, K. Y. (Invited speaker)
15 Nov 2025 → 19 Nov 2025Activity: Talk or presentation › Contributed
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Role of soluble sST2 in regulating neurodegeneration during aging
FU, K. Y. (Invited speaker)
15 Nov 2025 → 19 Nov 2025Activity: Talk or presentation › Contributed
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Spatial transcriptomic investigation of the molecular alterations in brain cells in association with amyloid plaques deposition in Alzheimer’s disease.
FU, K. Y. (Invited speaker)
15 Nov 2025 → 19 Nov 2025Activity: Talk or presentation › Contributed
Awards
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2021 Major Breakthrough of Neuroscience in China
IP, N.Y.-Y. (Recipient) & FU, K. Y. (Recipient), Jan 2021
Prize: Best Paper Award and Prize