Projects per year
Personal profile
Research interests
Biological Sciences - Structural biology
Biological Sciences - Cell biology
Biological Sciences - Membrane trafficking
Biological Sciences - Disease mechanisms
Biological Sciences - Cell biology
Biological Sciences - Membrane trafficking
Biological Sciences - Disease mechanisms
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Related documents
Education/Academic qualification
PhD in Chemistry, PhD, Harvard University
2016
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Collaborations and top research areas from the last five years
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Projects
- 3 Active
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Elucidating the role of ATAD1 in mitochondrial protein homeostasis
WANG, L. (PI)
1/01/25 → 31/12/27
Project: Research
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Structural investigation of ATAD1-mediated tail-anchored protein extraction on the outer mitochondrial membrane
WANG, L. (PI)
15/08/23 → 14/08/26
Project: Research
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Mechanistic Elucidation of Mitochondria Quality Control
WANG, L. (PI)
1/07/23 → 30/06/28
Project: Research
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A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling
Lawrence, R. E., Shoemaker, S. R., Deal, A., Sangwan, S., Anand, A. A., Wang, L., Marqusee, S. & Walter, P., Apr 2024, In: Nature Chemical Biology. 20, 4, p. 422-431 10 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access2 Citations (Scopus) -
A central helical switch controls integrated stress response signaling via eIF2B conformation and assembly
Deal, A., Marqusee, S., Shoemaker, S., Lawrence, R., Walter, P. & Wang, L., Feb 2023, NLM (Medline).Research output: Other contribution › peer-review
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A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
Subramanian, A., Wang, L., Moss, T., Voorhies, M., Sangwan, S., Stevenson, E., Pulido, E. H., Kwok, S., Chalkley, R. J., Li, K. H., Krogan, N. J., Swaney, D. L., Burlingame, A. L., Floor, S. N., Sil, A., Walter, P. & Mukherjee, S., Nov 2023, In: Nature Cell Biology. 25, 11, p. 1600-1615 16 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access14 Citations (Scopus) -
A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation
Boone, M., Wang, L., Lawrence, R. E., Frost, A., Walter, P. & Schoof, M., Apr 2022, In: eLife. 11, e76171.Research output: Contribution to journal › Journal Article › peer-review
Open Access4 Citations (Scopus) -
Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
Wang, L., Toutkoushian, H., Belyy, V., Kokontis, C. & Walter, P., May 2022, In: eLife. 11, e73941.Research output: Contribution to journal › Journal Article › peer-review
Open Access20 Citations (Scopus)