Projects per year
Personal profile
Research interests
Biotechnology - Chemical biology
Biological Sciences - Immunology
Biological Sciences - Cancer
Biotechnology - Computational biology
Related documents
Education/Academic qualification
PhD in Chemistry, PhD, The University of Chicago
2019
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 4 Active
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Clinical trial to evaluate chemical modifications on microbiome-derived cell-free RNA as novel biomarkers for early diagnosis of colorectal cancer (CRC) in the Chinese population
NG, S. S. M. (CoI) & ZHANG, L. (PI)
Health and Medical Research Fund
1/09/26 → 31/08/29
Project: Research
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Base-resolution quantitative sequencing methods to study the interactome of RNA chemical modifications
ZHANG, L. (PI)
National Natural Science Foundation of China
1/01/26 → 31/12/28
Project: Research
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Single-cell quantitative sequencing of mammalian epitranscriptome to investigate RNA pseudouridine modifications in human and mouse preimplantation development
CHAN, D. Y. L. (CoI) & ZHANG, L. (PI)
1/09/25 → 31/08/28
Project: Research
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Quantitative base-resolution sequencing technology to study biological functions of RNA modifications
ZHANG, L. (PI)
1/01/24 → 31/12/26
Project: Research
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Enzyme-mediated alkynylation enables transcriptome-wide identification of pseudouridine modifications
Wang, Y., Pajdzik, K., Zhao, Y., Ye, C., Stone, T., Zhang, L. S., Zhang, W., Assari, M., Zhao, W., Sepich-Poore, C., Dai, Q., Wang, K., Luo, M., Pan, T. & He, C., 13 May 2026, In: Nature Communications. 17, 1, 16 p., 4318.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Lectin-Directed Protein Aggregation Therapy toward Hyperfucosylated and Hypersialylated Metastatic Colorectal Cancers
HAN, X., LI, Y., LIU, Y., SHEN, S., SHEN, Y., ZHANG, L. & VONG, K., 17 Jul 2026, (E-pub ahead of print) In: Biomaterials Research. 30, 15 p., 0394.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Multi-omics and developmental comparison of direct and conventional warming methods in vitrified human and mouse cleavage-stage embryos
Wu, W., SHEN, Y., SHEN, S., Xu, M., Zhang, L., Fung, K. K., Chung, J., Ju, C.-W., Fok, E., ZHANG, L. & CHAN, D. Y. L., 6 Jul 2026, (E-pub ahead of print) In: Human Reproduction. 13 p., deag105.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species
Xu, L., SHEN, S., Zhang, Y., Guo, Z., Lu, B., Huang, J., Li, R., SHEN, Y., ZHANG, L. & Deng, X., 4 Jun 2026, In: eLife.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Serotonin Modulates Lineage Plasticity in Neuroendocrine Prostate Cancer via Epigenetic Reprogramming
Ji, Y., Ju, C. W., Chen, L., Shen, K., Su, R., Li, A., Liu, X., Liu, B., Zhang, X., Lyu, R., Xia, P., Li, H., Pan, Y., Liu, Y., Tse, M. H., Xue, Y., Qian, H., Jing, N., Zhu, H. H. & Wang, L. & 10 others, , 1 Apr 2026, In: Cancer Discovery. 16, 4, p. 760-780 21 p.Research output: Contribution to journal › Journal Article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus)
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Quantitative study of dynamic RNA epitranscriptome in human diseases
ZHANG, L. (Invited speaker)
2025Activity: Talk or presentation › Invited
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Quantitative study of dynamic RNA epitranscriptome in human diseases
ZHANG, L. (Invited speaker)
2025Activity: Talk or presentation › Invited
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Quantitative study of dynamic RNA epitranscriptome in human diseases
ZHANG, L. (Invited speaker)
2025Activity: Talk or presentation › Invited
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Quantitative study of dynamic RNA epitranscriptome in human diseases / Keynote Speaker
ZHANG, L. (Invited speaker)
2025Activity: Talk or presentation › Keynote