Projects per year
Personal profile
Research interests
Biotechnology - Drosophila tumor model
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Related documents
Education/Academic qualification
PhD in Molecular Biology, PhD, Princeton University
2010
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Dive into the research topics where Yan YAN is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigation of Unpaired 2 as a novel cell competition factor
YAN, Y. (PI)
1/07/24 → 30/06/27
Project: Research
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Stem cell-niche interactions in tissue maintenance and engineering
WU, A. R. (CoPI), WU, Z. (CoPI), WANG, C. C. (CoPI), ZHOU, Z. (CoPI), LEUNG, D. C. Y. (CoPI), FOK, E. K. L. (CoPI), GUO, Y. (CoPI), WANG, H. (CoPI), MAK, H. Y. (CoPI), LIU, K. (CoPI), SUN, F. (CoPI), YUNG, P.S.-H. (CoPI), CHEUNG, T. (CoPI), XIE, T. (PI), YAN, Y. (CoPI) & WEN, Z. (CoPI)
RGC - Theme-based Research Scheme
1/01/22 → 31/12/26
Project: Research
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Construction of an optogenetic system for precise control of Notch signaling
LI, M. (CoI), YAN, Y. (PI) & YANG, Y. (CoI)
24/11/20 → 30/11/23
Project: Research
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The crosstalk between the fat body and imaginal disc tumors suppresses tumor growth in a Drosophila tumor model
YAN, Y. (PI)
1/09/20 → 29/02/24
Project: Research
Research output
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Epigenetic reprogramming induced by key metabolite depletion is an evolutionarily ancient path to tumorigenesis
Chen, Z., Zhang, X., Deng, M., Li, C., Nguyen, T. T., Liu, M., Dou, K., Ishibashi, T., Wang, J. & Yan, Y., Jun 2025, In: DMM Disease Models and Mechanisms. 18, 6, dmm052313.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
H2B.W2, a spermatocyte-specific histone variant, disrupts nucleosome stability, and reduces chromatin compaction
Nguyen, A. T. T., Ding, D., Bai, X., Pang, M. Y. H., Deng, M., Liu, Y., Jin, T., Xu, Z., Zhang, Y., Zhai, Y., Yan, Y. & Ishibashi, T., 9 Sept 2025, In: Nucleic Acids Research. 53, 16, gkaf825.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Oncogenic Ras, Yki and Notch signals converge to confer clone competitiveness through Upd2
WANG, Y., HUANG, R., Deng, M., He, J., DENG, M., Ishibashi, T., Yu, C., Zhai, Z. & Yan, Y., 2 May 2025, (E-pub ahead of print) In: Journal of Genetics and Genomics.Research output: Contribution to journal › Journal Article › peer-review
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Epigenetic reprogramming induced by Acetyl-CoA and SAM depletion is an evolutionarily-ancient path to malignant growth
CHEN, Z., ZHANG, X., DENG, M., LI, C., NGUYEN, T. T., LIU, M., DOU, K., ISHIBASHI, T., WANG, J. & YAN, Y., Feb 2024, (bioRxiv).Research output: Working paper › Preprint
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Formation of destabilized nucleosome core particles by spermatogenesis-specific histone variant H2BFWT and its infertility-associated mutant H2BFWT-H100R: Insights from single-molecule optical tweezers and cryo-electron microscopy
Sun, X., Deng, M., Ding, D., Ishibashi, T., Liu, Y., Nguyen, T. T., Pang, Y. H. & Yan, Y., Feb 2024.Research output: Contribution to conference › Conference Paper › peer-review
Activities
- 2 Editorial work
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Journal of Genetics and Genomics (Journal)
YAN, Y. (Editorial Board Member)
1 Apr 2023 → 1 Apr 2026Activity: Publication peer-review and editorial work › Editorial work
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Hereditas(Beijing) (Journal)
YAN, Y. (Editor)
1 Jan 2020 → 1 Jan 2026Activity: Publication peer-review and editorial work › Editorial work