Projects per year
Personal profile
Research interests
Biotechnology - Synthetic Biology
Biotechnology - Microbiome Engineering
Biotechnology - Living Therapeutics and Diagnostics
Biotechnology - Genome Engineering
Biotechnology - Functional Metagenomics
Biotechnology - Microbiome Engineering
Biotechnology - Living Therapeutics and Diagnostics
Biotechnology - Genome Engineering
Biotechnology - Functional Metagenomics
Related documents
Education/Academic qualification
PhD in Microbiology, PhD, The University of Hong Kong
2016
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy -
SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
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Projects
- 1 Active
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Genome-wide CRISPR-Cas9 screen and synthetic gene circuits for inflammatory bowel disease therapy
LAI, Y. (PI)
1/01/24 → 31/12/26
Project: Research
Research output
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Flow perfusion via integrated vasculature drives human brain organoid maturation and enables modelling of microglia-vasculature trafficking
FENG, X., TAM, S. T., TAN, S. Y., WANG, X., LI, J., Cheng, L. K. W., ZHANG, H., HUANG, X., Leung, Z., KIM, H., Yang, H., XU, Y., WU, S., WAN, X., WANG, Y., LAI, Y., Zhang, J., MIAO, Y., YANG, C. & WANG, Y. & 1 others, , 13 May 2026.Research output: Contribution to conference › Conference Presentation
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CRISPR-based genetic tools for the study of host-microbe interactions
ECHAVARRIA GALINDO, M. & LAI, Y., 9 Sept 2025, In: Infection and Immunity. 93, 9, 20 p., e00510-24.Research output: Contribution to journal › Review article › peer-review
Open Access13 Link opens in a new tab Citations (Scopus) -
Flow Perfusion via Integrated Vasculature Drives Human Brain Organoid Maturation and Enables Modeling of Microglia-vasculature Trafficking
FENG, X., TAM, S. T., TAN, S. Y., WANG, X., LI, J., CHENG, K. W., ZHANG, H., HUANG, X., LEUNG, Z., KIM, H., YANG, H., XU, Y., WU, S., Wan, X., WANG, Y., LAI, Y., ZHANG, J. Z., MIAO, Y., YANG, C. & WANG, Y. & 1 others, , 7 Apr 2025, Cell Press, 141 p.Research output: Working paper › Preprint
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Proteomic study of Akkermansia muciniphila and Bifidobacterium species co-culture under different carbon sources
Sulaiman, J. E., Zhan, Y., Wang, S., Lai, K. L., Li, J. H. W., Yutong, D. Y., Tsim, K. W. K., Cheng, K. K. Y., Lai, Y. & Lam, H., 6 Nov 2025, In: Frontiers in Microbiology. 16, p. 1-15 15 p., 1666747.Research output: Contribution to journal › Journal Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Cas9-assisted biological containment of a genetically engineered human commensal bacterium and genetic elements
Hayashi, N., Lai, Y., Fuerte-Stone, J., Mimee, M. & Lu, T. K., Dec 2024, In: Nature Communications. 15, 1, 2096.Research output: Contribution to journal › Journal Article › peer-review
Open Access53 Link opens in a new tab Citations (Scopus)
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Perfusable vascularized human brain organoids
TAM, S. T. (Speaker), FENG, X. (Contributor), TAN, S. Y. (Contributor), WANG, X. (Contributor), LI, J. (Contributor), Cheng, L. K. W. (Contributor), ZHANG, H. (Contributor), HUANG, X. (Contributor), LEUNG, Z. (Contributor), KIM, H. (Contributor), YANG, H. (Contributor), XU, Y. (Contributor), WU, S. (Contributor), WAN, X. (Contributor), WANG, Y. (Contributor), LAI, Y. (Contributor), Zhang, J. Z. (Contributor), MIAO, Y. (Contributor), YANG, C. (Contributor), WANG, Y. (Contributor) & WU, A. R. (Contributor)
10 May 2026 → 15 May 2026Activity: Talk or presentation › Contributed
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mBio: the flagship journal of American Society for Microbiology (Journal)
LAI, Y. (Editorial Board Member)
1 Jan 2024 → 1 Dec 2025Activity: Publication peer-review and editorial work › Editorial work