Projects per year
Personal profile
Biography
Professor Yung Hou WONG, PhD
Professor Yung Hou Wong was appointed Dean of Science from 1 July 2022.
Prof. Wong is a Chair Professor in the Division of Life Science, while also serving as the Director of the Molecular Neuroscience Center and Associate Director of the Biotechnology Research Institute and the Center for Aging Science. He obtained his PhD in Pharmacology from the University of Cambridge and received postdoctoral training at the University of California San Francisco. Prof. Wong has assumed various major administrative positions at different levels since joining HKUST in 1992, including Associate Dean of the School of Science, Acting Head of the former Department of Biochemistry, Program Director, and Chair of numerous university committees.
Prof. Wong is an accomplished scholar in molecular pharmacology whose research interest focuses on the delineation of the mechanisms of cell signaling, particularly those involving the G protein-coupled receptors (GPCRs). Among his major research achievements, he has elucidated the molecular pharmacology of many GPCRs of therapeutic value, including those for opioid peptides, melatonin, and chemokines. Prof. Wong’s substantial contributions to the understanding of GPCRs in regulating gene transcription, cell proliferation and differentiation have far-reaching impacts beyond the academic arena.
As one of the prominent figures in the field, Prof. Wong has published over 220 scientific articles. He has been very active in the international academic community through his membership of major academic societies including the American Society for Biochemistry and Molecular Biology, International Society for Neurochemistry and the Asia-Pacific International Molecular Biology Network. He is also the Co-Editor-in-Chief of FASEB BioAdvances, an official journal published by the Federation of American Societies for Experimental Biology. Over the years, Prof. Wong has received a number of awards including the Croucher Senior Research Fellowship and the Medal of Honor by the Hong Kong SAR Government.
Prof. Wong has extensive connection and collaboration with the government, non-profit NGOs and industries on applied research initiatives and various public services. He has served in the Consumer Council of Hong Kong, the Medical Council of Hong Kong, and the Biomedical Technology Cluster Expert Panel of the Hong Kong Science and Technology Park.
Position Held
Director of Daniel and Mayce Yu Molecular Neuroscience Center
Acting Director of Institute for Health Innovation
Associate Director of Biotechnology Research Institute
Research interests
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Related documents
Education/Academic qualification
PhD in Pharmacology, PhD, University of Cambridge
1989
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Collaborations and top research areas from the last five years
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Preclinical Development of a TCM Formula for Alzheimer’s Disease Treatment
CHAN, S. L. A. (Team member), WONG, Y. H. (PI), FU, G. (CoI), SUNG, C. C. (Team member) & KAN, L. L. Y. (Team member)
1/01/26 → 31/12/27
Project: Research
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The Center for Neurodegenerative Diseases (HKCeND)
STEVENS, B. (PI), CHEN, Y. (PI), WU, Z. (PI), FU, K. Y. (PI), IP, F. C. F. (PI), IP, N.Y.-Y. (PI), FU, W. Y. (PI), WONG, Y. H. (PI), LEUNG, D. C. Y. (CoI), HARDY, J. (PI), WANG, J. (CoI), LIU, K. (CoI), CHAN, Y. C. P. (CoI), RANDO, T. A. (PI), YE, T. (PI), CHEUNG, T. (CoI) & HUANG, X. (CoI)
1/07/20 → 30/06/30
Project: Research
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Development of Next-Generation Anti-inflammatory and Anti-tussive Herbal Products
CHAN, S. L. A. (CoI), WONG, Y. H. (PI), WOO, W. Y. (CoI), LOW, C. K. J. (CoI) & HON, T. K. W. (CoI)
1/11/19 → 31/01/22
Project: Research
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Evaluation of the effectiveness of a traditional Chinese herbal formula (Yang Xin Tang) in the treatment of Alzheimer's disease
FU, K. Y. (CoI) & WONG, Y. H. (PI)
1/08/19 → 31/01/22
Project: Research
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Regulation of leukemia inhibitory factor (LIF) by G protein-coupled receptors (GPCRs) for intercellular communication between neurons and astrocytes
WONG, Y. H. (PI)
1/01/19 → 31/12/21
Project: Research
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Context-dependent switching of melatonin receptor signaling: MT1 and MT2 coupling from Gi to Gs
CHAN, H. Y., LEE, T. Y., KOT, Y. K. & WONG, Y. H., Jun 2025.Research output: Contribution to conference › Conference Paper
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Deciphering the role of Yang Xin Tang in modulating Gq-coupled receptor/Ca2+/PLC pathway
LO, T. Y., CHAN, A. S. L. & WONG, Y. H., Jun 2025.Research output: Contribution to conference › Conference Paper
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G Protein–Coupled Receptors in Skin Aging
Cheung, S. T., Do, Y., Kim, E., Rella, A., Goyarts, E., Pernodet, N. & Wong, Y. H., Apr 2025, In: Journal of Investigative Dermatology. 145, 4, p. 749-765.e8Research output: Contribution to journal › Review article › peer-review
2 Citations (Scopus) -
Activation of Bradykinin B2 Receptors in Astrocytes Stimulates the Release of Leukemia Inhibitory Factor for Autocrine and Paracrine Signaling
Lu, Y., Gu, Y., Chan, A. S. L., Yung, Y. & Wong, Y. H., Dec 2024, In: International journal of molecular sciences. 25, 23, 13079.Research output: Contribution to journal › Journal Article › peer-review
Open Access -
Analysis of metagenome and metabolome disclosed the mechanisms of Dendrobium officinale polysaccharide on DSS-induced ulcerative colitis-affected mice
Zeng, X., Tang, S., Dong, X., Dong, M., Shao, R., Liu, R., Li, T., Zhang, X., Wong, Y. H. & Xie, Q., Oct 2024, In: International Journal of Biological Macromolecules. 277, 134229.Research output: Contribution to journal › Journal Article › peer-review
19 Citations (Scopus)
Activities
- 19 Editorial work
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FASEB BioAdvances (Journal)
WONG, Y. H. (Chief Editor)
1 Jan 2022 → 1 Dec 2023Activity: Publication peer-review and editorial work › Editorial work
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FASEB BioAdvances (Journal)
WONG, Y. H. (Associate Editor)
1 Jan 2018 → 1 Jan 2021Activity: Publication peer-review and editorial work › Editorial work
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Science Focus (Journal)
WONG, Y. H. (Associate Editor)
1 Sept 2017 → …Activity: Publication peer-review and editorial work › Editorial work
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Frontiers in Endocrinology (Journal)
WONG, Y. H. (Associate Editor)
1 Mar 2017 → …Activity: Publication peer-review and editorial work › Editorial work
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FASEB J (Journal)
WONG, Y. H. (Reviewer)
1 Jan 2017 → …Activity: Publication peer-review and editorial work › Editorial work