新型移动式家庭电子尿流率仪和 Laborie尿流率仪临床检测结果比较

目的:设计移动式家庭电子尿流率仪检测系统并与传统的方法进行比较。方法:本研究设计的系统包括采集器、导流器、智能手机、无线网络通信技术、计算机分析和绘图、数据库存储技术等, 具备自动收集患者排尿信息的功能。患者排尿的信息由采集器经蓝牙发送到智能手机, 再由智能手机直接储存并无线发送到医院的工作站。对尿流率仪 (简称Laborie尿流率仪) 进行多次实验室单纯容量及临床患者实际尿流率测定并与Laborie尿流率仪进行比较, 采用Bland-Altman方法对两种尿流率仪的一致性进行评估, 测定了38例有下尿路症状的门诊患者, 其中男性22例, 女性16例, 年龄21～37岁, 平均年龄25.5岁。检查1次者19例, 2次者19例;共检查57次。结果:该系统能正确地收集和分析排尿时间、尿流率、尿量, 并自动报告尿流参数, 100、200、300、500和800 mL容量测定与正常值的误差均低于5%。最大尿流率、平均尿流率和排尿量分别有12.28%、5.26%和3.51%的点在95%可信区间以外, 而在可信区间内, 差值的最大绝对值分别为0.38 mL/s、0.70 mL/s和2.90 mL, 均符合国际尿控协会的规定。结论:新型移动式家庭电子尿流率仪与Laborie尿流率仪具有一致性, 是一个集准确可靠、实时方便和易管理于一体的崭新的检测系统。与传统的检查相比同样无创、可靠, 并具有可携带、可院外应用、可同时记录排尿日记的优点。Objective: To design a new portable home electronic uroflowmeter and compare it with traditional methods.Methods: The system consists of collectors, urine conducting apparatus, intelligent cell phone, wireless network communication technology, computer analysis and drawing, and data storage technology, etc., and can automatically collect voiding information from patients with lower urinary tract symptoms (LUTS) Through Bluetooth, the voiding information was sent to the patient's intelligent cell phone from the collector, then stored directly by intelligent cell phone and wirelessly transmitted to the workstation in hospital.The system was primarily tested with regard to accuracy of measurement of the voided volume.Multiple doses with known volume were introduced in the system and Laborie uroflowmeter.Furthermore, 38 outpatients who had LUTS were tested simultaneously with the system and Laborie uroflowmeter.The statistical method for assessing agreement between the two methods of clinical measurement was Bland-Altman analysis.Among the subjects, there were 22 male patients and 16 female patients, ranging from 21 to 37 years old, with an average age of 25.5 years, of whom, 19 were tested once and 19 patients twice, equaling to 57 tests.Results: The system could accurately collect and analyze voiding time, uroflowmetry, voided volume, and automatically provide uroflowmetry parameters.The measurement error of 100, 200, 300, 500 and 800 mL is less than 5%.12.28%, 5.26%and 3.51% of the Qmax, Qave and voided volume points were beyond the 95% limits of agreement.The maximum absolute values of the Qmax, Qave and voided volume difference were 0.38 mL/s, 0.70 mL/s and 2.90 mL, respectively.They agreed with the recommendation of Standardization International Continence Society.Conclusion: The new portable home electronic uroflowmeter has good agreement with Laborie uroflowmeter, and is a new LUTS monitoring system integrated with correct, reliable, real-time, convenient and easy-managing advantages.It is as noninvasive and reliable as traditional methods, and its portable feature facilitates application out of hospitals.It can also record voiding diaries.