A novel synthesis of 3,5-diiodotyrosine with iodic acid

Wangyi Liu*, Jianguang Zhou, J. Tze Fei Wong

*Corresponding author for this work

Research output: Contribution to journalJournal Articlepeer-review

Abstract

Based on Landolt's reaction between iodic acid and sulfite to produce iodine, a method has been developed for the high-yield iodination of tyrosine to form diiodotyrosine without significant formation of monoiodotyrosine. The use of sulfite as reductant for iodic acid cannot be effectively replaced by citric or oxalic acid under the reaction conditions.

Original languageEnglish
Pages (from-to)204-207
Number of pages4
JournalAnalytical Biochemistry
Volume120
Issue number1
DOIs
Publication statusPublished - Feb 1982
Externally publishedYes

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