Abstract
PGC-1 regulates energy homeostasis and mitochondrial activity. In this issue, Rera et al. (2011) show that dPGC-1 overexpression in Drosophila intestinal stem cells and their immediate progeny extends organismal life span and protects against age-related loss of intestinal homeostasis and integrity, thereby establishing a link between mitochondria, tissue stem cells, and aging.
| Original language | English |
|---|---|
| Pages (from-to) | 571-572 |
| Number of pages | 2 |
| Journal | Cell Metabolism |
| Volume | 14 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2 Nov 2011 |
| Externally published | Yes |