Application of generic principles of process intensification to solution crystallization enabled by a task-based design approach

Richard Lakerveld*, Herman J.M. Kramer, Andrzej I. Stankiewicz, Johan Grievink

*Corresponding author for this work

Research output: Contribution to journalJournal Articlepeer-review

18 Citations (Scopus)

Abstract

The design of current industrial crystallizers is strongly focussed on optimization of known types of crystallization equipment. These crystallizers harbour various physical phenomena, which are strongly entangled. The application of generic principles of process intensification (PI) to crystallization processes requires individual control over physical phenomena. A new design method is applied that exploits elementary processing functions as building blocks for design instead of existing equipment, which enables the application of generic principles of PI. Innovations in the field of crystallization to manipulate shear forces, manipulate nucleation rates with external fields, and improve control over solvent removal with membranes are key technologies. A case study demonstrates the application of task-based design for solution crystallization. The results show how task-based design leads to high modularization of the process representation and model architecture. In addition, task-based design enables the application of generic PI principles, which results in a large flexibility to manipulate final product quality. Future needs include generalization of task-based design for crystallization and development of novel technologies for single task manipulation.

Original languageEnglish
Pages (from-to)979-991
Number of pages13
JournalChemical Engineering and Processing: Process Intensification
Volume49
Issue number9
DOIs
Publication statusPublished - Sept 2010
Externally publishedYes

Keywords

  • Crystallization
  • Dynamic optimization
  • Membranes
  • Nucleation
  • Process intensification
  • Task-based design
  • Ultrasound

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