TY - JOUR
T1 - Asymmetric Wittig reaction of chiral arsonium ylides - I. Asymmetric olefination of 4-substituted cyclohexanones
AU - Dai, Wei Min
AU - Wu, Jinlong
AU - Huang, Xian
PY - 1997/6/27
Y1 - 1997/6/27
N2 - Asymmetric Wittig-type olefination of 4-substituted cyclohexanones with chiral ligand-modified stable arsonium ylides has been examined. The 8-phenylmenthol-derived chiral arsonium ylide of 4 reacted with prochiral ketones 9a-d at -15°C to give the 4-substituted cyclohexylideneacetates 11a-d in 58-69% yield and in up to 80% diastereomeric excess (de).
AB - Asymmetric Wittig-type olefination of 4-substituted cyclohexanones with chiral ligand-modified stable arsonium ylides has been examined. The 8-phenylmenthol-derived chiral arsonium ylide of 4 reacted with prochiral ketones 9a-d at -15°C to give the 4-substituted cyclohexylideneacetates 11a-d in 58-69% yield and in up to 80% diastereomeric excess (de).
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:A1997XJ79100010
UR - https://openalex.org/W2065877124
UR - https://www.scopus.com/pages/publications/0030958790
U2 - 10.1016/S0957-4166(97)00223-1
DO - 10.1016/S0957-4166(97)00223-1
M3 - Journal Article
SN - 0957-4166
VL - 8
SP - 1979
EP - 1982
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 12
ER -