@inbook{b22c77a39bda40029d0ed7133436f714,
title = "Bioinformatic analysis of data generated from MALDI mass spectrometry for biomarker discovery",
abstract = "In this chapter we first describe the applications of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) in biomarker discovery. After a summary of the general analysis pipeline of MALDI MS data, each step of the pipeline will be elaborated in detail. In particular we try to provide a categorization of existing solutions with the hope that the reader can obtain a global picture on this topic. In addition we show how to apply such an analysis pipeline in protein and glycan profiling for biomarker discovery and for a deeper understanding of diseases. Finally we discuss the limitations of current analysis methods and the perspectives of future research.",
keywords = "Biomarker Discovery, Data Mining, Feature Selection, MALDI MS Data, Peak Detection",
author = "Zengyou He and Qi, \{Robert Z.\} and Weichuan Yu",
year = "2013",
doi = "10.1007/128-2012-365",
language = "English",
isbn = "9783642356643",
series = "Topics in Current Chemistry",
pages = "193--210",
editor = "Zongwei Cai and Shuying Liu",
booktitle = "Applications of MALDI-TOF Spectroscopy",
}