Clustering acetylcholine receptors in neuromuscular junction by phase-separated Rapsn condensates

Guanhua Bai; Mingjie Zhang

doi:10.1016/j.neuron.2021.05.024

Clustering acetylcholine receptors in neuromuscular junction by phase-separated Rapsn condensates

Guanhua Bai, Mingjie Zhang^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

2 Citations (Scopus)

Abstract

In this issue of Neuron, Xing et al. (2021) demonstrate that the multidomain scaffold protein Rapsn can form dense molecular condensates in vitro and in vivo via phase separation. The formation of Rapsn condensates is essential for clustering acetylcholine receptors on muscle membranes and for forming neuromuscular junctions.

Original language	English
Pages (from-to)	1907-1909
Number of pages	3
Journal	Neuron
Volume	109
Issue number	12
DOIs	https://doi.org/10.1016/j.neuron.2021.05.024
Publication status	Published - 16 Jun 2021
Externally published	Yes

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© 2021 Elsevier Inc.

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10.1016/j.neuron.2021.05.024

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title = "Clustering acetylcholine receptors in neuromuscular junction by phase-separated Rapsn condensates",

abstract = "In this issue of Neuron, Xing et al. (2021) demonstrate that the multidomain scaffold protein Rapsn can form dense molecular condensates in vitro and in vivo via phase separation. The formation of Rapsn condensates is essential for clustering acetylcholine receptors on muscle membranes and for forming neuromuscular junctions.",

author = "Guanhua Bai and Mingjie Zhang",

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AU - Bai, Guanhua

AU - Zhang, Mingjie

PY - 2021/6/16

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N2 - In this issue of Neuron, Xing et al. (2021) demonstrate that the multidomain scaffold protein Rapsn can form dense molecular condensates in vitro and in vivo via phase separation. The formation of Rapsn condensates is essential for clustering acetylcholine receptors on muscle membranes and for forming neuromuscular junctions.

AB - In this issue of Neuron, Xing et al. (2021) demonstrate that the multidomain scaffold protein Rapsn can form dense molecular condensates in vitro and in vivo via phase separation. The formation of Rapsn condensates is essential for clustering acetylcholine receptors on muscle membranes and for forming neuromuscular junctions.

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000663531600001

UR - https://openalex.org/W3169519825

UR - https://www.scopus.com/pages/publications/85107940606

U2 - 10.1016/j.neuron.2021.05.024

DO - 10.1016/j.neuron.2021.05.024

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SN - 0896-6273

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SP - 1907

EP - 1909

JO - Neuron

JF - Neuron

IS - 12

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Clustering acetylcholine receptors in neuromuscular junction by phase-separated Rapsn condensates

Abstract

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