Skip to main navigation Skip to search Skip to main content

Corrigendum: A fast and powerful W-test for pairwise epistasis testing

  • Junfeng Guo
  • , Jack Lee
  • , Rui Sun
  • , Maggie Haitian Wang*
  • , Haoyi Weng
  • , Benny Chung-Ying Zee
  • , Pak Chung Sham
  • , Inchi Hu
  • *Corresponding author for this work

Research output: Other contributionpeer-review

Abstract

The authors wish to make the following correction to their article: In this paper the authors describe a novel method, the W-test, which provides an association test with data-set adaptive probability distributions that measures epistasis for both common and low frequency SNPs. The article compares W-test to three alternative methods, namely the logistic regression, Chi-squared test, and MDR. All methods are computed using existing R packages. The authors did not realize that the MDR package is different from the original version of MDR (1). The original version of MDR does not support the evaluation of exhaustive pair-wise for the one million replications reported in the study. The MDR simulation results reported in the article must therefore be removed from the article. The results of the W-test, logistic regression and Chi-square are not affected, and the conclusion of the article remains valid. A new manuscript that excludes the MDR analysis is available as supplementary material. The authors apologize to the readers for the inconvenience caused.
Original languageEnglish
PublisherOxford Univ Press
Publication statusPublished - 2016

Publication series

NameNucleic Acids Research
PublisherOxford Univ Press
ISSN (Print)03051048
ISSN (Electronic)'13624962

Fingerprint

Dive into the research topics of 'Corrigendum: A fast and powerful W-test for pairwise epistasis testing'. Together they form a unique fingerprint.

Cite this