TY - JOUR
T1 - Enzyme-instructed self-assembly of peptide derivatives to form nanofibers and hydrogels.
AU - Gao, Yuan
AU - Yang, Zhimou
AU - Kuang, Y.
AU - Ma, Man Lung
AU - Li, Jiayang
AU - Zhao, Fan
AU - Xu, Bing
PY - 2010
Y1 - 2010
N2 - The review describes the use of enzyme catalysis and self-assembly, two essential and ubiquitous processes in biology, to create molecular nanofibers of peptide derivatives at the supramolecular level as potential nanomedicines and biomaterials. In particular, we discuss the use of enzymes to instruct the self-assembly of small peptide derivatives for hydrogelation, which takes place in vitro or in vivo, extra- or intracellularly, as a new strategy to detect the activity of enzymes, screen enzyme inhibitors, type bacteria, develop drug delivery systems, enhance the activity and stability of enzymes, and control the fate of cells. (c) 2010 Wiley Periodicals, Inc.
AB - The review describes the use of enzyme catalysis and self-assembly, two essential and ubiquitous processes in biology, to create molecular nanofibers of peptide derivatives at the supramolecular level as potential nanomedicines and biomaterials. In particular, we discuss the use of enzymes to instruct the self-assembly of small peptide derivatives for hydrogelation, which takes place in vitro or in vivo, extra- or intracellularly, as a new strategy to detect the activity of enzymes, screen enzyme inhibitors, type bacteria, develop drug delivery systems, enhance the activity and stability of enzymes, and control the fate of cells. (c) 2010 Wiley Periodicals, Inc.
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000274422500003
UR - https://openalex.org/W1965741679
UR - https://www.scopus.com/pages/publications/77950365247
U2 - 10.1002/bip.21321
DO - 10.1002/bip.21321
M3 - Review article
C2 - 20091873
SN - 0006-3525
VL - 94
SP - 19
EP - 31
JO - Biopolymers
JF - Biopolymers
IS - 1
ER -