Experimental measurement and modeling analysis of active and passive mechanical properties of arterial vessel wall

Yundi Feng, Hao Wu, Yunlong Huo

Research output: Contribution to journalJournal Articlepeer-review

Abstract

心血管疾病(CAD)已经严重威胁着人类健康。对血管壁力学性质的实验测量和建模分析可以为疾病的诊断、支架的植入,以及人工血管的设计等提供理论依据。动脉血管壁有主动和被动的力学性能,被动力学性能主要由弹性纤维和胶原蛋白纤维的含量和结构决定;主动力学性能则由平滑肌细胞(VSMC)的收缩实现。大量研究表明,动脉血管壁的双层膜结构模型可以很好地反映血管的力学性能,血管壁的周向、轴向、径向应力都有重要作用。本文综述了近年来血管壁力学性质测量和力学性能建模方面的研究进展,以及该研究方向面临的挑战和机遇,以期为临床心血管疾病的治疗提供支持。.

Original languageEnglish
Pages (from-to)939-947
Number of pages9
Journal生物医学工程学杂志=Journal of biomedical engineering
Volume37
Issue number6
DOIs
Publication statusPublished - 25 Dec 2020
Externally publishedYes

Keywords

  • cardiovascular mechanics
  • stress and strain
  • vessel wall active mechanical properties
  • vessel wall constitutive model
  • vessel wall passive mechanical properties

Fingerprint

Dive into the research topics of 'Experimental measurement and modeling analysis of active and passive mechanical properties of arterial vessel wall'. Together they form a unique fingerprint.

Cite this