Fabrication and self-assembly of movable microstructures embedding cells inside microfluidic devices

Tao Yue*, Masahiro Nakajima, Chengzhi Hu, Yajing Shen, Hirotaka Tajima, Toshio Fukuda

*Corresponding author for this work

Research output: Chapter in Book/Conference Proceeding/ReportConference Paper published in a bookpeer-review

1 Citation (Scopus)

Abstract

Currently the research about large quantities cells assembly is seriously regarded, since it can provide high efficiency methods for artificial tissue engineering. In this paper, we report a cell assembly method based on cell immobilization by photo-crosslinkable resin and microfluidic self-assembly inside microfluidic devices. The on-chip fabrication of movable microstructures embedding yeast cells (W303) based on Poly (ethylene glycol) Diacrylate (PEGDA) was reported. A 2-layer microfluidic device was fabricated by Polydimethylsiloxane (PDMS) and self-assembly method of the fabricated movable microstructures via this device was preliminarily demonstrated.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages1153-1155
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012
Externally publishedYes
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 28 Oct 20121 Nov 2012

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Conference

Conference16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
Country/TerritoryJapan
CityOkinawa
Period28/10/121/11/12

Keywords

  • Microfluidic device
  • On-chip fabrication
  • Self-assembly
  • Tissue engineering

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