Feasibility of MoS₂ for analytical and bioanalytical applications

Molybdenum disulfide (MoS₂) received recognition from the scientific community due to its high absorbance in the NIR region, superior physiological and biocompatibility traits, high fluorescence quenching ability, and fluorescence emission feature, making it suitable for analytical and bioanalytical applications. In this review, we highlighted salient traits of MoS₂ that accelerate its feasibility for analytical sciences. The particular bandgap of 1.8 eV in its monolayers and layer-dependence of band structures tackle the gapless problems of graphene, enhancing its scientific and industrial importance. The characteristic electronic structure and low cyto- and genotoxicity profiles, tunable structure, and surface functionalization of MoS₂ compared to other transition metal dichalcogenides render it feasible for next-generation optoelectronics, analytical, biomedical, and point-of-care applications. To fully unleash the potential of MoS₂, the era demands to fabrication of facile, cost-effective, and tunable synthesis approaches, exploring their structure-activity relationship, and investigating strategies for integrating with trending techniques including synthetic biology and machine learning.