Hydrogenation of Aldehydes Catalyzed by an Available Ruthenium Complex

Xuefeng Tan; Guozhen Wang; Ziyue Zhu; Conghui Ren; Jinping Zhou; Hui Lv; Xiaoyong Zhang; Lung Wa Chung; Lina Zhang; Xumu Zhang

doi:10.1021/acs.orglett.6b00060

Hydrogenation of Aldehydes Catalyzed by an Available Ruthenium Complex

Xuefeng Tan, Guozhen Wang, Ziyue Zhu, Conghui Ren, Jinping Zhou, Hui Lv, Xiaoyong Zhang, Lung Wa Chung^*, Lina Zhang, Xumu Zhang

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

45 Citations (Scopus)

Abstract

A readily available ruthenium(II) catalyst was developed for the catalytic hydrogenation of aldehydes with a TON (turnover number) up to 340000. It can be performed without base and solvent, showing highly industrial potential. High chemoselectivity can be achieved in the presence of alkenyl and ketone groups. Further application of this protocol in glucose reduction showed good efficiency. Theoretical studies revealed that the rate-determining step is the hydrogenation step, not the carboxylate-assisted H₂ activation step.

Original language	English
Pages (from-to)	1518-1521
Number of pages	4
Journal	Organic Letters
Volume	18
Issue number	7
DOIs	https://doi.org/10.1021/acs.orglett.6b00060
Publication status	Published - 15 Apr 2016
Externally published	Yes

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© 2016 American Chemical Society.

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abstract = "A readily available ruthenium(II) catalyst was developed for the catalytic hydrogenation of aldehydes with a TON (turnover number) up to 340000. It can be performed without base and solvent, showing highly industrial potential. High chemoselectivity can be achieved in the presence of alkenyl and ketone groups. Further application of this protocol in glucose reduction showed good efficiency. Theoretical studies revealed that the rate-determining step is the hydrogenation step, not the carboxylate-assisted H2 activation step.",

author = "Xuefeng Tan and Guozhen Wang and Ziyue Zhu and Conghui Ren and Jinping Zhou and Hui Lv and Xiaoyong Zhang and Chung, \{Lung Wa\} and Lina Zhang and Xumu Zhang",

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T1 - Hydrogenation of Aldehydes Catalyzed by an Available Ruthenium Complex

AU - Tan, Xuefeng

AU - Wang, Guozhen

AU - Zhu, Ziyue

AU - Ren, Conghui

AU - Zhou, Jinping

AU - Lv, Hui

AU - Zhang, Xiaoyong

AU - Chung, Lung Wa

AU - Zhang, Lina

AU - Zhang, Xumu

PY - 2016/4/15

Y1 - 2016/4/15

N2 - A readily available ruthenium(II) catalyst was developed for the catalytic hydrogenation of aldehydes with a TON (turnover number) up to 340000. It can be performed without base and solvent, showing highly industrial potential. High chemoselectivity can be achieved in the presence of alkenyl and ketone groups. Further application of this protocol in glucose reduction showed good efficiency. Theoretical studies revealed that the rate-determining step is the hydrogenation step, not the carboxylate-assisted H2 activation step.

AB - A readily available ruthenium(II) catalyst was developed for the catalytic hydrogenation of aldehydes with a TON (turnover number) up to 340000. It can be performed without base and solvent, showing highly industrial potential. High chemoselectivity can be achieved in the presence of alkenyl and ketone groups. Further application of this protocol in glucose reduction showed good efficiency. Theoretical studies revealed that the rate-determining step is the hydrogenation step, not the carboxylate-assisted H2 activation step.

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000373519600006

UR - https://openalex.org/W2300065652

UR - https://www.scopus.com/pages/publications/84963967647

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M3 - Journal Article

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VL - 18

SP - 1518

EP - 1521

JO - Organic Letters

JF - Organic Letters

IS - 7

ER -

Hydrogenation of Aldehydes Catalyzed by an Available Ruthenium Complex

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