Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method

Xianlong Zhang; Xiaoling Wang; Qingping Sun

doi:10.1016/j.piutam.2017.06.003

Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method

Xianlong Zhang, Xiaoling Wang^*, Qingping Sun

^*Corresponding author for this work

Department of Mechanical and Aerospace Engineering

Research output: Contribution to journal › Conference article published in journal › peer-review

1 Citation (Scopus)

Abstract

Various types of bacterial form adhesive aggregates on surfaces known as biofilms, which are of interest to researchers in a great variety of fields. In this paper, a continuum model based on diffusion-reaction is proposed and extended finite element method (XFEM) coupled to level set is employed to simulate the biofilm growth on ager substrate. Numerical results show the quantitative relationship between colony morphology and nutrient deletion. Comparing with experiment observation, we approve that diffusion limited regime is more appropriate than growth limited regime to describe Bacillus subtilis biofilm growth on MSgg ager substrate. Our model can be extended to investigate detailed biological process in biofilm growth such as cell subdivision and osmotic pressure induced transportation.

Original language	English
Pages (from-to)	33-41
Number of pages	9
Journal	Procedia IUTAM
Volume	23
DOIs	https://doi.org/10.1016/j.piutam.2017.06.003
Publication status	Published - 2017
Event	IUTAM Symposium on Growing solids, 2015 - Moscow, Russian Federation Duration: 23 Jun 2015 → 27 Jun 2015

Bibliographical note

Publisher Copyright:
© 2017 The Authors.

Keywords

Bacillus subtilis
XFEM
ager substrate
biofilm growth
diffusion limited regime

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10.1016/j.piutam.2017.06.003

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@article{4222be721a894714b342ae03f82a5267,

title = "Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method",

abstract = "Various types of bacterial form adhesive aggregates on surfaces known as biofilms, which are of interest to researchers in a great variety of fields. In this paper, a continuum model based on diffusion-reaction is proposed and extended finite element method (XFEM) coupled to level set is employed to simulate the biofilm growth on ager substrate. Numerical results show the quantitative relationship between colony morphology and nutrient deletion. Comparing with experiment observation, we approve that diffusion limited regime is more appropriate than growth limited regime to describe Bacillus subtilis biofilm growth on MSgg ager substrate. Our model can be extended to investigate detailed biological process in biofilm growth such as cell subdivision and osmotic pressure induced transportation.",

keywords = "Bacillus subtilis, XFEM, ager substrate, biofilm growth, diffusion limited regime",

author = "Xianlong Zhang and Xiaoling Wang and Qingping Sun",

note = "Publisher Copyright: {\textcopyright} 2017 The Authors.; IUTAM Symposium on Growing solids, 2015 ; Conference date: 23-06-2015 Through 27-06-2015",

year = "2017",

doi = "10.1016/j.piutam.2017.06.003",

language = "English",

volume = "23",

pages = "33--41",

journal = "Procedia IUTAM",

issn = "2210-9838",

}

TY - JOUR

T1 - Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method

AU - Zhang, Xianlong

AU - Wang, Xiaoling

AU - Sun, Qingping

PY - 2017

Y1 - 2017

N2 - Various types of bacterial form adhesive aggregates on surfaces known as biofilms, which are of interest to researchers in a great variety of fields. In this paper, a continuum model based on diffusion-reaction is proposed and extended finite element method (XFEM) coupled to level set is employed to simulate the biofilm growth on ager substrate. Numerical results show the quantitative relationship between colony morphology and nutrient deletion. Comparing with experiment observation, we approve that diffusion limited regime is more appropriate than growth limited regime to describe Bacillus subtilis biofilm growth on MSgg ager substrate. Our model can be extended to investigate detailed biological process in biofilm growth such as cell subdivision and osmotic pressure induced transportation.

AB - Various types of bacterial form adhesive aggregates on surfaces known as biofilms, which are of interest to researchers in a great variety of fields. In this paper, a continuum model based on diffusion-reaction is proposed and extended finite element method (XFEM) coupled to level set is employed to simulate the biofilm growth on ager substrate. Numerical results show the quantitative relationship between colony morphology and nutrient deletion. Comparing with experiment observation, we approve that diffusion limited regime is more appropriate than growth limited regime to describe Bacillus subtilis biofilm growth on MSgg ager substrate. Our model can be extended to investigate detailed biological process in biofilm growth such as cell subdivision and osmotic pressure induced transportation.

KW - Bacillus subtilis

KW - XFEM

KW - ager substrate

KW - biofilm growth

KW - diffusion limited regime

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000418402800003

UR - https://openalex.org/W2751020336

UR - https://www.scopus.com/pages/publications/85030456278

U2 - 10.1016/j.piutam.2017.06.003

DO - 10.1016/j.piutam.2017.06.003

M3 - Conference article published in journal

SN - 2210-9838

VL - 23

SP - 33

EP - 41

JO - Procedia IUTAM

JF - Procedia IUTAM

T2 - IUTAM Symposium on Growing solids, 2015

Y2 - 23 June 2015 through 27 June 2015

ER -

Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method

Abstract

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Keywords

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