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Synthesis of trisubstituted-4H-pyrans via unexpected cycloaddition of aldehydes with acetylenic ketones mediated by DMAP and 2, 4-pentanedione

  • Bin Hu
  • , Qing Fa Zhou*
  • , Kai Tang
  • , Song Xue
  • *Corresponding author for this work

Research output: Contribution to journalJournal Articlepeer-review

Abstract

A cycloaddition of aldehydes and acetylenic ketones mediated by 4-dimethylaminopyridine and 2, 4- pentanedione is reported. The method supplies a facile way to synthesize 3, 4, 5-trisubstituted-4H-pyrans in moderate to good yields under mild conditions.

Original languageEnglish
Pages (from-to)560-563
Number of pages4
JournalLetters in Organic Chemistry
Volume6
Issue number7
DOIs
Publication statusPublished - Oct 2009
Externally publishedYes

Keywords

  • 2, 4-pentanedione
  • 4H-pyran
  • Acetylenic ketones
  • Aldehydes
  • Cycloaddition
  • DMAP

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