TY - JOUR
T1 - WDSPdb
T2 - An updated resource for WD40 proteins
AU - Ma, Jing
AU - An, Ke
AU - Zhou, Jing Bo
AU - Wu, Nuo Si
AU - Wang, Yang
AU - Ye, Zhi Qiang
AU - Wu, Yun Dong
N1 - Publisher Copyright:
© 2019 The Author(s).
PY - 2019/11/1
Y1 - 2019/11/1
N2 - The WD40-repeat proteins are a large family of scaffold molecules that assemble complexes in various cellular processes. Obtaining their structures is the key to understanding their interaction details. We present WDSPdb 2.0, a significantly updated resource providing accurately predicted secondary and tertiary structures and featured sites annotations. Based on an optimized pipeline, WDSPdb 2.0 contains about 600 thousand entries, an increase of 10-fold, and integrates more than 37 000 variants from sources of ClinVar, Cosmic, 1000 Genomes, ExAC, IntOGen, cBioPortal and IntAct. In addition, the web site is largely improved for visualization, exploring and data downloading.
AB - The WD40-repeat proteins are a large family of scaffold molecules that assemble complexes in various cellular processes. Obtaining their structures is the key to understanding their interaction details. We present WDSPdb 2.0, a significantly updated resource providing accurately predicted secondary and tertiary structures and featured sites annotations. Based on an optimized pipeline, WDSPdb 2.0 contains about 600 thousand entries, an increase of 10-fold, and integrates more than 37 000 variants from sources of ClinVar, Cosmic, 1000 Genomes, ExAC, IntOGen, cBioPortal and IntAct. In addition, the web site is largely improved for visualization, exploring and data downloading.
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000501728500049
UR - https://www.scopus.com/pages/publications/85074964426
U2 - 10.1093/bioinformatics/btz460
DO - 10.1093/bioinformatics/btz460
M3 - Journal Article
C2 - 31161214
SN - 1367-4803
VL - 35
SP - 4824
EP - 4826
JO - Bioinformatics
JF - Bioinformatics
IS - 22
ER -